Executive Health Programs Compared: Mayo, Cleveland, Fountain Life, HLI, Biograph

Two different products

Academic Executive Health vs. Longevity Platform

Mayo and Cleveland Clinic executive health programs deliver a one-time deep evaluation: 1–3 days of testing, imaging, and same-visit subspecialist consultations at a major academic medical center. The model is built around episodic comprehensive workup, not ongoing care.

Fountain Life, HLI, and Biograph deliver an annual membership: imaging plus longitudinal coordination with a longevity-focused care team. The model is built around continuous monitoring and intervention, not one-shot evaluation.

These are different products. Many high-end patients use both — a Mayo or Cleveland visit every 2–3 years for the deep academic look, plus a longevity platform membership for the annual cadence.

Mayo

Mayo Clinic Executive Health Program

Mayo's executive health program runs 1–3 days at Rochester MN, Jacksonville FL, or Scottsdale AZ. Typical scope includes comprehensive labs, advanced lipid panel, screening colonoscopy or alternatives, cardiac workup (often calcium score, stress testing), pulmonary function, dermatology screen, and consultations as indicated.

Cost: roughly $6,000–$15,000 per assessment depending on location and scope. Some services bill to insurance; the program-level fee does not. Whole-body MRI is an optional add-on at additional cost.

Strengths: academic depth, access to Mayo subspecialists in the same week if anything is found, and the brand-level reputation that helps with second opinions.

Cleveland Clinic

Cleveland Clinic Executive Health Program

Cleveland Clinic's executive health is similar in structure to Mayo's: 1–3 day comprehensive assessment with same-week subspecialist access. Particular strength in cardiovascular workup given Cleveland Clinic's cardiology reputation.

Cost: roughly $6,000–$12,000 per assessment. Insurance billing of individual covered services applies.

Fountain Life

Fountain Life Apex Membership

Annual membership at approximately $10,500/year (verified June 2026; varies by location). Locations include Naples FL, Dallas TX, Orlando FL, Houston TX, and New York. Includes whole-body MRI, coronary CT angiography, full-body DEXA, comprehensive labs, grip-strength and VO2 max testing, and a longevity-physician care team.

Position: the most accessible price point in the full-service longevity-clinic category. Founder branding (Tony Robbins, Peter Diamandis) drives strong consumer awareness.

Human Longevity Institute

Human Longevity Institute — 100+ Health Nucleus

Initial assessment ~$25,000 for the 100+ Health Nucleus comprehensive evaluation (verified June 2026); annual follow-up ~$15,000–$25,000 depending on scope. Single location in La Jolla, CA.

Distinct features: whole-genome sequencing, whole-body MRI with proprietary AI imaging analysis, coronary CT, cognitive assessment, comprehensive labs, and a multidisciplinary physician panel.

Position: the most genomics-forward platform. Founder J. Craig Venter pedigree underlies the sequencing depth.

Biograph

Biograph

Annual cost ~$15,000/year (verified June 2026). San Francisco-headquartered with announced expansion. Includes whole-body MRI, advanced cardiac imaging, comprehensive longevity labs (ApoB, Lp(a), inflammation, hormones), continuous glucose monitoring, VO2 max testing, and concierge follow-up.

Position: tech-forward design and software experience; popular among Bay Area founders and tech executives.

Decision framework

How to Choose Between Them

• ·Want academic-grade comprehensive evaluation with subspecialist access? Mayo or Cleveland Clinic.
• ·Want an annual longevity-forward platform with imaging at the most accessible price? Fountain Life.
• ·Want the most genomics-forward platform and willing to pay for it? HLI.
• ·Bay Area patient who values the software experience and tech-forward design? Biograph.
• ·Want both? Many patients combine a Mayo or Cleveland visit every 2–3 years with an annual Fountain Life or Biograph membership in the off-years.