Longevity Medicine
What Is Hyperbaric Oxygen Therapy?
Last reviewed: May 2026 · Haute MD Editorial Team
Hyperbaric oxygen therapy (HBOT) involves breathing 100% pure oxygen in a pressurized chamber at 1.5-3x normal atmospheric pressure, dissolving oxygen into the bloodstream at much higher concentrations. FDA-cleared for wound healing, decompression sickness, and CO poisoning. A 2020 Tel Aviv study showed 60 HBOT sessions produced 20% telomere elongation and reduced senescent cells.
Approved and emerging uses
FDA-cleared indications include chronic non-healing wounds, decompression sickness, carbon monoxide poisoning, and radiation injury. Emerging research investigates HBOT for traumatic brain injury, post-stroke recovery, and longevity outcomes.
Typical longevity protocol
Research protocols typically involve 40-60 sessions of 90 minutes at 2.0 ATA over 2-3 months. Outcomes studied include cognitive function, telomere length, and senescent cell burden.
Frequently Asked Questions
Is HBOT safe?
When delivered in a medical-grade chamber under supervision, HBOT is safe. Risks include ear barotrauma and rarely oxygen toxicity at higher pressures.
Is HBOT covered by insurance?
Insurance covers FDA-approved indications. Off-label longevity use is typically out of pocket.
How long is a session?
Most clinical sessions last 60-90 minutes. Longevity protocols typically involve multiple sessions per week.
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Longevity Medicine · New York, NY
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