Longevity Medicine
What Blood Tests Are Important for Longevity?
Last reviewed: May 2026 · Haute MD Editorial Team
The most important blood tests for longevity go well beyond the standard CBC and basic metabolic panel. The essential longevity panel includes ApoB, Lp(a), fasting insulin and HOMA-IR, hsCRP, comprehensive hormonal panel (testosterone, DHEA-S, thyroid), vitamin D, ferritin, omega-3 index, and homocysteine. Together these provide a comprehensive picture of cardiovascular, metabolic, hormonal, and inflammatory health.
Cardiovascular blood tests
ApoB, Lp(a), NMR lipid panel (LDL particle number and size), hsCRP, oxidized LDL, homocysteine, NT-proBNP.
Metabolic blood tests
Fasting insulin, HOMA-IR, HbA1c, fasting glucose, comprehensive metabolic panel, uric acid, GGT.
Hormonal blood tests
Total and free testosterone, SHBG, estradiol, DHEA-S, TSH, free T3, free T4, reverse T3, morning cortisol, IGF-1.
Nutritional blood tests
Vitamin D (25-OH), vitamin B12, folate, ferritin, magnesium (RBC), zinc, omega-3 index, homocysteine.
Frequently Asked Questions
Will my doctor order these tests?
Standard primary care physicians may not routinely order all of these. A longevity physician is more likely to order a comprehensive panel. You can also order many tests directly through Function Health, LabCorp Direct, or Quest Diagnostics.
How often should I get a longevity blood panel?
Most longevity physicians recommend quarterly during active health optimization and twice yearly for maintenance once results are stable.
What is the most important blood test I can add to standard labs?
ApoB and Lp(a) are the most impactful additions. They provide cardiovascular risk information unavailable from standard cholesterol testing.
What is Function Health?
A direct-to-consumer advanced health testing service that orders and interprets 100+ biomarkers without requiring a physician visit.
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Longevity Medicine · Miami Beach, FL
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Longevity Medicine · New York, NY
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Longevity Medicine · New York, NY
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