Haute Beauty | October 1, 2025

Where To Book the Coveted Salmon DNA Treatment

Haute Beauty | October 1, 2025
Darby Kordonowy
By Darby Kordonowy, Freelance Writer
Skinbooster DNA Salmon

Photo Credit: Medica DepotSalmon DNA facials, often dubbed “salmon sperm facials” for their use of PDRN (polydeoxyribonucleotide) from salmon DNA, have emerged as a cutting-edge rejuvenation trend in high-end skincare. Since salmon DNA is ~97% match to human DNA, it’s highly biocompatible and triggers deep regeneration, strengthening the skin barrier, improving elasticity, and calming inflammation. Check out these leading clinics and med spas in Boston, Miami, New York, Los Angeles, Chicago, Dallas, and Naples offering innovative salmon DNA facials.

Photo Credit: Canadian Medical Center

ALXS SKN GYM
Owner and award-winning esthetician Alexis Robertson of ALXS SKN GYM celebrated for her bespoke approach to skincare, brings more than 20 years of expertise to the beauty industry. Her signature treatment, the ‘Glowy B/Mermaid Facial’ is a 60-minute treatment using microneedling to infuse polynucleotides that boost hydration, smooth texture, and repair skin at the cellular level. It includes dermaplaning, numbing, PDRN serum microchanneling, and an oxygenating mask to enhance absorption resulting in tighter, glowing skin with diminished lines and pores immediately after.

297 Newbury St Suite 3, Boston, MA 02115

Skn Elements 
Skn Elements led by Caleb McGrew offers their PDRN “Salmon Sperm” Microneedling treatment, a Korean-imported PDRN facial combining microneedling with a salmon DNA serum for dramatic skin rejuvenation. After cleansing and numbing, Skn Elements uses a PDRN-rich ‘Healing Essence’ (salmon sperm DNA in a sealed syringe) applied via microneedling. The PDRN serum derived from ethically “massaged” salmon, is packed with amino acids, hyaluronic acid, and bioavailable polynucleotides that boost collagen, smooth fine lines, and deeply hydrate the skin. Red LED light therapy and a tightening cellulose mask are used post-needling to lock in benefits. Clients describe their skin as tight, glowy, and like a facelift after this treatment. Book this as a standalone treatment, and the PDRN serum can also be added onto other facials for a boost.

7295 NW 2nd Ave, Miami, FL 33150

Dr. Jennifer Levine 
Dr. Jennifer Levine, a double board-certified facial plastic surgeon and Vice Chair of the AAFPRS Emerging Trends Committee, offers the PDRN Therapy: Salmon DNA Rejuvenation, a clinical-grade salmon DNA skin booster as a post-procedure enhancement. Dr. Levine applies a PDRN serum made with Nucleoskin, containing polynucleotides from salmon sperm plus hyaluronic acid and glutathione, immediately after RF microneedling or laser resurfacing when microchannels are open. This topical PDRN infusion capitalizes on the skin’s receptivity post-laser to stimulate collagen, improve elasticity and skin texture, and impart a youthful glow. Many patients pair it with procedures like Fraxel, Morpheus8, Sciton, and Nordlys for skin repair, or even post-surgeries, including blepharoplasty, facelift, and rhinoplasty, to accelerate recovery and boost results. 

Ste B, 240 E 79th St, New York, NY 10075

Kanodia MedSpa
Kanodia MedSpa is the medspa arm of Dr. Raj Kanodia, a famed Beverly Hills plastic surgeon known for a focus on non-surgical innovation. The med spa’s PDRN Salmon DNA Facial is a cutting-edge regenerative facial that harnesses highly purified salmon DNA applied after aggressive procedures to accelerate healing and amplify results. The PDRN serum, rich in polynucleotides, is used after Morpheus8 and Potenza CO2 treatments, soaking into the freshly treated skin to boost collagen, reduce inflammation, and speed up recovery. The medspa also pairs PDRN with advanced exosome technology for synergistic rejuvenation. Exosomes act as cellular messengers, enhancing the penetration and effectiveness of regenerative compounds deep within the skin. 

414 N Camden Dr., Beverly Hills, CA

Chicago Aesthetics Med Spa 
NIH-funded researcher and award-winning facial plastic surgeon Dr. John D. Rachel who leads Chicago Aesthetics Med Spa. The med spa offers the VAMP™ Salmon Salmon Sperm Facial, an advanced microneedling facial enhanced with PDRN derived from wild salmon, vitamins, amino acids, and polynucleotides. The polynucleotide-rich serum (95% similar to human DNA) triggers intensive cellular repair, collagen production, and deep hydration to improve tone, texture, and elasticity. This facial is often combined with MOXI, Morpheus8, chemical peels, or laser resurfacing.

1 E Erie St., Chicago, IL (Magnificent Mile area).

EpiCentre Skin Care & Laser Center 
EpiCentre Skin Care & Laser Center, Dallas’s premier medical spa, affiliated with the renowned Dallas Plastic Surgery Institute, offers the Korean Salmon DNA Treatment. This Rejuran PN/PDRN therapy is offered as an add-on or a standalone facial. This treatment uses Rejuran Healing Essence, a polynucleotide serum derived from wild salmon sperm DNA to rejuvenate skin from within. The procedure can be done on its own or immediately after procedures like SkinPen microneedling, Halo/MOXI laser, or chemical peels to enhance their effects. EpiCentre providers apply the Rejuran serum into microchannels in the skin, often followed by LED therapy. Patients notice reduced redness, faster healing, and a lasting glow. Common targets are fine lines, dullness, enlarged pores, and acne scars. 

9101 N. Central Expressway, Dallas, TX

Naples Skin Clinic 
Naples Skin Clinic is recognized for delivering clinical-grade results without surgery. Founded and operated by Bita Ardakani-Akrawi, PA-C, a board-certified Physician Assistant and cosmetic dermatology specialist with more than 15 years of experience. Known for its “biohacking” approach to skincare, the clinic offers cutting-edge facials such as the Vamp PDRN Salmon Sperm Facial, an advanced anti-aging therapy that uses purified salmon DNA (PDRN) serum combined with exosomes. This gentle yet powerful treatment helps stimulate collagen production, brighten the complexion, and smooth fine lines and uneven texture. For enhanced results, it is often paired with microneedling to allow for deeper penetration.

3960 Radio Rd STE 109, Naples, FL 34104

Glow On The Go: At-Home With Salmon DNA Product

Each of these at-home skincare products allows you to harness the power of salmon DNA for skin rejuvenation. Regular use can help hydrate, repair, and revitalize the skin’s appearance.

Rejuran Turnover Mask
Infused with Aloe Vera, Adenosine, and the patented Rejuran powerhouse ingredient c-PDRN®, this concentrated microfiber sheet mask delivers calming, reparative benefits to nurture and strengthen skin overnight, leaving it healthy-looking, balanced, and revitalized.

Rejuran Turnover Mask

Photo Credit: Rejuran

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Biodance Rejuvenating Caviar PDRN Real Deep Mask
This hydrogel mask combines caviar extract with PDRN to restore and rejuvenate your skin while you sleep, deeply hydrating and strengthening the barrier.

Biodance Rejuvenating Caviar PDRN Real Deep Mask

Photo Credit: Biodance

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REJURAN® Turnover Ampoule
Reveal radiant, youthful skin with c-PDRN®, a marine-based growth factor combined with hydrating hyaluronic acid to improve tone, texture, and radiance while supporting natural collagen production. This advanced serum helps calm and revitalize damaged skin, diminish the look of wrinkles, sun damage, and scars, refine pores, and boost lasting moisture for a luminous glow.

REJURAN® Turnover Ampoule

Photo Credit: REJURAN®

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DERMALINE D’LEXO PDRN Solution Salmon Ampoule
This ampoule fortifies the skin’s moisture barrier with salmon-derived PDRN, Hyaluronic Acid, and Centella Asiatica to deliver deep hydration, soothing care, and enhanced resilience. Niacinamide helps fade dark spots for a brighter, more even complexion.

DERMALINE D’LEXO PDRN Solution Salmon Ampoule

Photo Credit: Dermaline

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