From the Inside Out: How Sofwave Supports Patients on GLP-1s

Photo Credit: Sofwave

The rise of GLP-1 medications like Ozempic, Wegovy, and Mounjaro has sparked a transformative shift in how we approach weight loss. These drugs have helped millions shed pounds, improve their metabolic health, and regain confidence. But, there’s one side effect that’s become harder to ignore: “Ozempic Face.”

As patients lose weight rapidly, especially in the face, many notice deflated cheeks, sagging jawlines, and fine lines that seem to appear overnight. It’s not just fat loss—it’s skin breakdown in skin structure.

Before and After by Saltz Plastic Surgery

“GLP-1 medications can be incredibly effective for weight loss, but the changes often show up first in the face,” explains Dr. Renato Saltz, board-certified plastic surgeon in Utah. “As volume decreases quickly, patients—both men and women—notice hollowing, sagging, and deeper lines. These effects are magnified in Utah’s dry climate, which accelerates skin thinning and moisture loss, making volume loss more visible.”

In fact, new research suggests that GLP-1 drugs may alter how stem cells function, reducing their ability to create fibroblasts and pre-adipocytes—both essential for producing collagen and elastin. Without them, skin loses its resilience.

Dr. Jean Carruthers

“Our facial skin is supported by our facial fat, by our facial muscles, and by our facial bony skeleton. When we lose support from bone and fat remodeling from aging, we expect this to happen gradually,” adds Dr. Jean Carruthers, oculoplastic surgeon and founder of Carruthers Cosmetic. “With the rapid weight loss stimulated by the GLP-1 drugs, the skin can not keep up with the new need for more elastin and collagen.”

That’s where Sofwave comes in.

FDA-cleared and non-invasive, Sofwave uses cutting-edge ultrasound technology to stimulate the skin’s natural collagen and elastin production. With just one 45-minute session, patients begin seeing improvement in 12 weeks—with no downtime, no needles, and no disruption to their lifestyle.

Photo Credits: Dr. Carruthers

“Sofwave is an excellent tool to support patients as they lose weight. It stimulates collagen and elastin regeneration, which helps restore firmness and lift in the skin,” says Dr. Saltz. “The results are natural and progressive, with improvements in facial definition and overall skin quality. Sofwave can also be used on the body—areas like the arms, thighs, and abdomen—where loose skin often appears after weight loss. When combined with good skincare, hydration, and lifestyle habits, Sofwave helps patients maintain healthier, more resilient skin through the changes that come with GLP-1 treatment.”

Dr. Renato Saltz

Dr. Carruthers agrees: “The energy used is ultrasound, so Sofwave can be applied to skin of every tone. The treatment tip has no needles, so people can go straight back to their regular work and social activities. Usually, we do 3 treatments spaced a month apart, and we see the results about 3 months after the last treatment.”

Photo Credits: Dr. Carruthers

And the benefits extend beyond the face. Sofwave is equally effective on the body, targeting loose skin on the arms, thighs, and abdomen, which are common areas of concern after weight loss.

Ultimately, this is about more than beauty—it’s about balance.

GLP-1s help patients feel better from the inside out. Sofwave helps ensure they still recognize the person they see in the mirror.