Our Editors Say This is the Skincare Brand Actually Changing How Luxury Skincare Works

We’ve said it before, and we will say it again: there’s no one quite like Amy Peterson in Miami—or the industry. Every season brings a new wave of skincare launches promising clinical results, but Lenox and Sixteenth is proving efficacy beyond results  — and the reason starts with its founder. Peterson, a celebrity medical aesthetician, built the brand around a specific gap she saw in her own clinical practice: the difference between what happens during an in-office treatment and what a person can actually sustain at home.

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However, it’s Peterson’s skin philosophy that truly sets her apart. In fact, I will never forget the moment I stepped into her office in 2021 – a sense of relief immediately came over me. I remember thinking, finally someone who is actually looking at my skin – and my skin only. Peterson is the epitome of a beauty professional who does not believe in one-size-fits-all. And somehow, Peterson has successfully bottled her ethos in Lenox and Sixteenth.

For me, Lenox and Sixteenth is intentional. It is built to close that treatment-room-to-bathroom-cabinet gap directly. Every formula is engineered as a layered system rather than a single active ingredient, brightening, strengthening, hydrating, repairing, protecting, and resurfacing through multiple biological pathways at once. Peterson’s formulation approach rests on five core technologies: Multi-Peptide Architecture, Dual Vitamin C Technology, Triple Acid Resurfacing, Biomimetic Barrier Science, and Intelligent Recovery, each chosen for function rather than trend, designed to work without compromising the skin barrier in the process.

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The brand’s two defining claims are deliberately specific about what they are and aren’t. “Treatment Strength” refers to formulating with clinically recognized cosmetic ingredients at concentrations meaningful enough to deliver visible results, not drug-strength, prescription, or professionally administered treatment, but a cosmetic formula built to perform beyond basic moisturizing. “Zero Recovery,” meanwhile, addresses the downtime associated with in-office procedures like lasers, chemical peels, or resurfacing: no irritation, no peeling, no recovery period. That standard extends across the ingredient list, too: Leaping Bunny Certified and cruelty-free, with every formula fragrance-free, paraben-free, sulfate-free, phthalate-free, and formaldehyde-free.

The lineup itself centers on a handful of standouts. The Laser Serum Triple Acid Concentrate and The Preservationist Vitamin C Cream Serum are the brand’s two best-sellers, joined by Soft Landing Smoothing Peptide Moisturizer and the newly launched Prep Pads Daily Skin Conditioning System, a conditioning step meant to prime skin before the rest of the routine.

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Lenox and Sixteenth is closing a gap the skincare industry has left open for years: the space between what an in-office treatment can deliver and what a person can sustain at home without downtime or dilution. Most clinical-grade lines force a choice between the two. Peterson built her formulas on the premise that they shouldn’t have to, and it’s a premise other brands in the category are starting to follow suit.