The Reset Your Body Has Been Waiting For: EBO2 at Cellebration
George Kaltner, Cellebration, Sunny Isles Beach, FL
George Kaltner — Founder & CEO, Cellebration (Sunny Isles Beach and Miami Beach, FL).
Photo Credit: Cellebration
Before you commit to a major wellness protocol, a new aesthetic procedure, or a serious regenerative treatment, there is one question worth asking: is your body actually ready to receive it? EBO2, the blood filtration and ozonation treatment offered at Cellebration in Sunny Isles Beach, answers that question with a yes. It is not a treatment in the traditional sense. It helps filter the blood and create a more prepared physiological environment, supporting the body's response to subsequent interventions.
EBO2, also known as EBOO, stands for Extracorporeal Blood Oxygenation and Ozonation. In the procedure, blood is drawn from one arm, run through an external circuit with a filter, exposed to an oxygen-ozone gas mixture (and, at some clinics, ultraviolet light), and returned to the body. Cellebration describes a session as taking about 90 minutes. Clinics that offer EBO2 say the filter removes inflammatory proteins, heavy metals and other waste; those claims have not been confirmed in controlled clinical trials.
What EBO2 Actually Does
The filtration step is what Cellebration says sets EBO2 apart from simpler ozone therapies: blood passes through a filter before it is exposed to ozone. Published research has not yet shown what the filter removes in a way that improves health.
The ozonation step triggers what researchers describe as a controlled oxidative response. Ozone is a highly reactive form of oxygen. Proponents theorize that a brief, controlled oxidative stress prompts the body's antioxidant defenses, but that has not been shown to improve immune function, energy or cellular repair in well-designed human trials. FDA regulations describe ozone as "a toxic gas with no known useful medical application in specific, adjunctive, or preventive therapy" (21 CFR 801.415).
The treatment's relationship to subsequent protocols is where Cellebration's clinical philosophy becomes most relevant. Cellebration offers EBO2 as a preparatory step before other regenerative and aesthetic treatments. That sequencing reflects the clinic's philosophy; there is no published evidence that EBO2 makes later injectables or regenerative treatments work better.
The Science Behind the Reset
EBO2 is steadily gaining interest from those seeking integrative approaches to health, well-being, and regenerative medicine. Interest in EBO2 is growing, but the research base is small. One randomized trial, published in 2005, compared EBOO with intravenous prostacyclin in 28 patients with peripheral artery disease and found improvement in skin lesions and symptoms, but no measurable change in blood flow to the legs (Di Paolo et al., International Journal of Artificial Organs, 2005). A 2025 case report in Cureus described a single 88-year-old patient whose urinary toxin measurements fell after two series of treatments; the authors noted there was no control for ongoing exposure (Bennett et al., Cureus, 2025). Neither study shows that EBO2 removes heavy metals, cholesterol plaques or toxins from the blood in a way that improves health.
The body of research continues to develop, and the treatment is not yet a mainstream medical protocol. EBO2 is not a mainstream or guideline-recommended treatment. Practitioners at Cellebration say they have seen patients respond well when EBO2 comes before other protocols; those are clinic observations, not results from controlled studies. Because the procedure involves an external blood circuit and exposing blood to ozone gas, anyone considering it should review the risks with their own physician first.
Who EBO2 Is For
Cellebration says it offers EBO2 to adults who are preparing for a wellness or aesthetic protocol. EBO2 has not been shown to treat fatigue, "brain fog," inflammatory conditions or environmental toxicity, and symptoms like these call for a medical evaluation.
It is not a treatment for acute illness and is not positioned as a replacement for conventional medical care. A thorough intake consultation at Cellebration will assess your candidacy and ensure the treatment is appropriate for your specific health profile before any session is scheduled.
EBO2 at Cellebration
Cellebration is a regenerative wellness clinic located in Sunny Isles Beach, Florida, offering a comprehensive portfolio of advanced therapies for longevity, recovery, and whole-body optimization. The clinic is rooted in the conviction that the most effective wellness outcomes begin with a body that has been properly prepared to receive treatment. EBO2 is one of the treatments the clinic offers as part of that philosophy.
Medical disclaimer: This article is for general information only and is not medical advice. EBO2 (EBOO) has not been shown to be safe and effective in large controlled clinical trials, and FDA regulations describe ozone as a toxic gas with no known useful medical application (21 CFR 801.415). Talk with a licensed physician about the risks before considering any procedure that removes, treats and returns your blood.
Learn more about George Kaltner and Cellebration, explore the Haute MD regenerative medicine network, or browse the full Haute MD physician directory.